How to Increase Leptin Levels

How to Increase Leptin Levels
How to Increase Leptin Levels

   How to Increase Leptin Levels

How to Increase Leptin Levels. Leptin is an appetite and energy intake regulation hormone. With adequate leptin levels, your hunger pangs should diminish for longer and you are less likely to overeat.

Low leptin levels make weight loss harder. This is because this hormone signals your brain that you do not have enough energy, thus decreasing how quickly calories will burn off.

How to Increase Leptin Levels Exercise

Regular physical exercise has been found to enhance many aspects of health, from weight loss and lower disease risks (like heart disease or type 2 diabetes ) to improving strength, flexibility, endurance, enhancing mood enhancement and adding years to one’s lifespan! Exercise offers tangible health benefits no matter your age or gender! A healthy lifestyle can improve quality of life.

How to Increase Leptin Levels. Leptin, produced by white adipose tissue (the main type of fat in your body), serves several functions within the body. Primarily it regulates hunger and satiation while also impacting metabolism, endocrine system regulation and immune function.

Studies have demonstrated that obesity and weight gain can reduce leptin levels, leading to an increased desire for food and resulting in an increase in leptin levels, thus contributing to weight gain and other health complications. It’s a very common phenomenon which contributes to people becoming obese as well as experiencing health issues related to their obesity.

Researchers speculate that moderate exercise could contribute to weight loss by decreasing leptin levels; they speculate this occurs as exercise helps your body utilize calories more efficiently, leading to reduced leptin levels and thus weight reduction over time.

Leptin has also been demonstrated to affect fatty acid metabolism in skeletal muscle, which is essential for maintaining an efficient energy balance and combatting chronic inflammatory disorders. Thus, leptin should not be underestimated!

Healthy Oils

Oils are an integral component of healthy eating, providing numerous health benefits and helping to increase leptin levels. It is crucial to select appropriate oils for different cooking methods and recipes.

Make sure your chosen oil can withstand high heat; olive oil is an ideal option, as its high smoke point allows it to withstand high temperatures without burning or smoking.

At all costs, it is wise to opt for unrefined oils extracted from plants and seeds using natural methods as much as possible, and avoid chemically refined and hydrogenated fats as much as possible.

Olive, sesame, grapeseed and canola oils are excellent choices for healthy eating, boasting high concentrations of monounsaturated and polyunsaturated fatty acids that may help decrease inflammation.

Vegetable oils can also be an effective choice, providing antioxidants that may help to decrease inflammation. Furthermore, vegetable oils help promote a healthy gut microbiome which may aid in controlling appetite.

Vegetable-rich diets can help to increase leptin levels. Packed with essential vitamins and minerals that will support optimal body functioning and overall wellbeing, vegetables are an excellent source of fiber which will slow digestion of carbs while keeping blood sugar steady.

Berries

Berries are an excellent source of vitamin C, which can help increase metabolism. Furthermore, they’re packed with fibre and water that will keep you feeling full for longer – not to mention activating leptin to accelerate weight loss and speed up metabolism!

Berries can be divided into two distinct groups: true berries and modified berries. To be considered a true berry, a fruit must have thin outer skin, fleshy center and jelly-like interior that contains seeds – so bananas, avocados and cucumbers don’t qualify.

Genetic modification has allowed some plants to produce fruit with greater anthocyanin concentration than most berries – like maqui berry. These fruits boast several times more anthocyanins.

Another study has discovered that eating polyphenol-rich berries can reduce appetite and boost leptin levels, as well as provide antioxidant benefits that may help fight disease and decrease cancer risks.

Leptin is an essential hormone in maintaining energy balance and maintaining healthy weight, and plays an integral part in warding off chronic illnesses such as diabetes and cardiovascular disease. Research shows that obesity reduces levels of leptin, so eating food that boosts these levels such as berries, legumes, whole grains and vegetables may help promote weight loss by increasing leptin sensitivity – something regular exercise can also do!

Legumes

Legumes such as beans, chickpeas and lentils provide ideal protein sources for those on diets low in fat and cholesterol. Plus they’re loaded with fiber which helps bind toxins in your gut and promote better digestion; plus they contain significantly fewer calories than animal proteins!

Oatmeal can help with weight loss because it helps you feel full. Plus, its potassium-rich composition helps regulate blood pressure and lower the risk of heart disease and cancer.

To maximize the nutritional benefits of legumes, soak them overnight before cooking – this will decrease phytic acid levels and allow your body to more readily absorb all of their vital minerals.

Some legumes, like white and kidney beans, require longer soaking times than you may be used to. Although this can be challenging for those accustomed to quick-cooking foods, the effort will pay off!

By adding legumes to your diet, you will increase leptin levels in your system, making weight loss easier. Plus, these seeds and beans contain many essential nutrients that support good health!

Eating legumes may reduce your risk of colorectal cancer as they contain high amounts of dietary fiber, micronutrients, and phytochemicals that could prevent cancer cells from forming in your colon.

Whole Grains

Diets that include whole grains can help increase leptin levels, providing an additional aid in weight loss. Leptin is produced naturally by our bodies and plays a key role in appetite regulation; additionally it can promote feelings of fullness after each meal and provide greater satisfaction overall.

Substituting whole grains for refined carbohydrates can help lower the risk of obesity and diabetes by providing essential nutrients like fiber, B vitamins, iron, copper zinc magnesium as well as phytochemicals and antioxidants that can reduce inflammation.

Wheat, rye breads, oat and barley porridge and other cereals can provide an excellent source of whole grain foods. When shopping, look out for products labeled ‘whole’ to ensure that their label indicates how many whole grains the item contains.

Grains consist of three layers, the bran, germ and endosperm. While the first two provide fibre, while the latter houses all of its nutrients that make up its composition.

The health benefits of whole grains depend on their species and cultivar. Oats and barley contain more soluble fibre while wheat and rye have higher amounts of insoluble fibre content.

Numerous studies have demonstrated that whole grains can help lower risk for obesity and cardiovascular disease, yet their benefits vary between study designs, perhaps due to differences in population or type of whole grain consumed.

Vegetables

Vegetables are an integral component of a nutritious diet, containing low amounts of fat and calories while boasting high amounts of fiber, vitamins, and antioxidants that help fight against disease.

Leptin, produced by fat cells, helps control body weight and energy levels by communicating with the appetite center of the brain to inform it that no food needs to be eaten immediately – instead calories will burn at their normal rate instead.

To raise leptin levels, it’s best to focus on eating plenty of vegetables while limiting sugary food like sodas, candy bars, processed meats with added sugar or saturated or trans fats as well as any beverages that contain caffeine or artificial sweeteners.

Additionally, you should decrease your carbs consumption and increase dietary fiber consumption to help lower triglycerides while increasing leptin sensitivity.

Fruit is an excellent source of dietary fiber and an ideal way to replace sugary beverages for snacking on. Choose watermelons, melons, berries, grapefruit and grapes as snacks to lower triglyceride levels and increase leptin levels in your system.

Dark green vegetables can help curb appetites and bring blood sugar levels down by providing essential fiber, folate and carotenoids, vitamin C and iron. Popular dark green vegetable options include broccoli, kale, collard greens, spinach and mustard greens.

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How to Increase Leptin Levels

How to Increase Leptin Levels
How to Increase Leptin Levels

   How to Increase Leptin Levels

How to Increase Leptin Levels. Leptin is an appetite and energy intake regulation hormone. With adequate leptin levels, your hunger pangs should diminish for longer and you are less likely to overeat.

Low leptin levels make weight loss harder. This is because this hormone signals your brain that you do not have enough energy, thus decreasing how quickly calories will burn off.

How to Increase Leptin Levels Exercise

Regular physical exercise has been found to enhance many aspects of health, from weight loss and lower disease risks (like heart disease or type 2 diabetes ) to improving strength, flexibility, endurance, enhancing mood enhancement and adding years to one’s lifespan! Exercise offers tangible health benefits no matter your age or gender! A healthy lifestyle can improve quality of life.

How to Increase Leptin Levels. Leptin, produced by white adipose tissue (the main type of fat in your body), serves several functions within the body. Primarily it regulates hunger and satiation while also impacting metabolism, endocrine system regulation and immune function.

Studies have demonstrated that obesity and weight gain can reduce leptin levels, leading to an increased desire for food and resulting in an increase in leptin levels, thus contributing to weight gain and other health complications. It’s a very common phenomenon which contributes to people becoming obese as well as experiencing health issues related to their obesity.

Researchers speculate that moderate exercise could contribute to weight loss by decreasing leptin levels; they speculate this occurs as exercise helps your body utilize calories more efficiently, leading to reduced leptin levels and thus weight reduction over time.

Leptin has also been demonstrated to affect fatty acid metabolism in skeletal muscle, which is essential for maintaining an efficient energy balance and combatting chronic inflammatory disorders. Thus, leptin should not be underestimated!

Healthy Oils

Oils are an integral component of healthy eating, providing numerous health benefits and helping to increase leptin levels. It is crucial to select appropriate oils for different cooking methods and recipes.

Make sure your chosen oil can withstand high heat; olive oil is an ideal option, as its high smoke point allows it to withstand high temperatures without burning or smoking.

At all costs, it is wise to opt for unrefined oils extracted from plants and seeds using natural methods as much as possible, and avoid chemically refined and hydrogenated fats as much as possible.

Olive, sesame, grapeseed and canola oils are excellent choices for healthy eating, boasting high concentrations of monounsaturated and polyunsaturated fatty acids that may help decrease inflammation.

Vegetable oils can also be an effective choice, providing antioxidants that may help to decrease inflammation. Furthermore, vegetable oils help promote a healthy gut microbiome which may aid in controlling appetite.

Vegetable-rich diets can help to increase leptin levels. Packed with essential vitamins and minerals that will support optimal body functioning and overall wellbeing, vegetables are an excellent source of fiber which will slow digestion of carbs while keeping blood sugar steady.

Berries

Berries are an excellent source of vitamin C, which can help increase metabolism. Furthermore, they’re packed with fibre and water that will keep you feeling full for longer – not to mention activating leptin to accelerate weight loss and speed up metabolism!

Berries can be divided into two distinct groups: true berries and modified berries. To be considered a true berry, a fruit must have thin outer skin, fleshy center and jelly-like interior that contains seeds – so bananas, avocados and cucumbers don’t qualify.

Genetic modification has allowed some plants to produce fruit with greater anthocyanin concentration than most berries – like maqui berry. These fruits boast several times more anthocyanins.

Another study has discovered that eating polyphenol-rich berries can reduce appetite and boost leptin levels, as well as provide antioxidant benefits that may help fight disease and decrease cancer risks.

Leptin is an essential hormone in maintaining energy balance and maintaining healthy weight, and plays an integral part in warding off chronic illnesses such as diabetes and cardiovascular disease. Research shows that obesity reduces levels of leptin, so eating food that boosts these levels such as berries, legumes, whole grains and vegetables may help promote weight loss by increasing leptin sensitivity – something regular exercise can also do!

Legumes

Legumes such as beans, chickpeas and lentils provide ideal protein sources for those on diets low in fat and cholesterol. Plus they’re loaded with fiber which helps bind toxins in your gut and promote better digestion; plus they contain significantly fewer calories than animal proteins!

Oatmeal can help with weight loss because it helps you feel full. Plus, its potassium-rich composition helps regulate blood pressure and lower the risk of heart disease and cancer.

To maximize the nutritional benefits of legumes, soak them overnight before cooking – this will decrease phytic acid levels and allow your body to more readily absorb all of their vital minerals.

Some legumes, like white and kidney beans, require longer soaking times than you may be used to. Although this can be challenging for those accustomed to quick-cooking foods, the effort will pay off!

By adding legumes to your diet, you will increase leptin levels in your system, making weight loss easier. Plus, these seeds and beans contain many essential nutrients that support good health!

Eating legumes may reduce your risk of colorectal cancer as they contain high amounts of dietary fiber, micronutrients, and phytochemicals that could prevent cancer cells from forming in your colon.

Whole Grains

Diets that include whole grains can help increase leptin levels, providing an additional aid in weight loss. Leptin is produced naturally by our bodies and plays a key role in appetite regulation; additionally it can promote feelings of fullness after each meal and provide greater satisfaction overall.

Substituting whole grains for refined carbohydrates can help lower the risk of obesity and diabetes by providing essential nutrients like fiber, B vitamins, iron, copper zinc magnesium as well as phytochemicals and antioxidants that can reduce inflammation.

Wheat, rye breads, oat and barley porridge and other cereals can provide an excellent source of whole grain foods. When shopping, look out for products labeled ‘whole’ to ensure that their label indicates how many whole grains the item contains.

Grains consist of three layers, the bran, germ and endosperm. While the first two provide fibre, while the latter houses all of its nutrients that make up its composition.

The health benefits of whole grains depend on their species and cultivar. Oats and barley contain more soluble fibre while wheat and rye have higher amounts of insoluble fibre content.

Numerous studies have demonstrated that whole grains can help lower risk for obesity and cardiovascular disease, yet their benefits vary between study designs, perhaps due to differences in population or type of whole grain consumed.

Vegetables

Vegetables are an integral component of a nutritious diet, containing low amounts of fat and calories while boasting high amounts of fiber, vitamins, and antioxidants that help fight against disease.

Leptin, produced by fat cells, helps control body weight and energy levels by communicating with the appetite center of the brain to inform it that no food needs to be eaten immediately – instead calories will burn at their normal rate instead.

To raise leptin levels, it’s best to focus on eating plenty of vegetables while limiting sugary food like sodas, candy bars, processed meats with added sugar or saturated or trans fats as well as any beverages that contain caffeine or artificial sweeteners.

Additionally, you should decrease your carbs consumption and increase dietary fiber consumption to help lower triglycerides while increasing leptin sensitivity.

Fruit is an excellent source of dietary fiber and an ideal way to replace sugary beverages for snacking on. Choose watermelons, melons, berries, grapefruit and grapes as snacks to lower triglyceride levels and increase leptin levels in your system.

Dark green vegetables can help curb appetites and bring blood sugar levels down by providing essential fiber, folate and carotenoids, vitamin C and iron. Popular dark green vegetable options include broccoli, kale, collard greens, spinach and mustard greens.

How Long Does It Take To Raise Leptin Levels, How To Boost Leptin In The Female Body, How To Boost Leptin Levels For Weight Loss, How To Increase Leptin And Adiponectin, How To Increase Leptin And Reduce Ghrelin, How To Increase Leptin And Serotonin, How To Increase Leptin Hormone In Women’s Body, How To Increase Leptin In The Body, How To Increase Leptin Levels, How To Increase Leptin Levels In Body, How To Increase Leptin Levels In The Body, How To Increase Leptin Levels To Lose Weight, How To Increase Leptin Levels With Supplements, How To Increase Levels Of Leptin, How To Keep Leptin Levels Up, How To Reduce Leptin In The Body, How To.increase Leptin

How to increase leptin

Increase Leptin
How To Increase Leptin

How to increase leptin steps you can take

How to increase leptin: When it comes to losing weight, fat, carbohydrates and fat are given the most attention. However, most of us tend to overlook the importance of hormones, especially leptin. Leptin plays an important role in managing weight.

Often referred to as the satiety hormone, leptin is directly connected to your weight and the amount of fat there is in your body. If the levels of leptin are low, it causes an inability to feel full which leads to feeling hungry all the time. What’s more, leptin resistance is a common occurrence which prevents your body from effectively responding to the hormone.

What is leptin?

Leptin is a hormone produced by the fat or adipose cells of the body. The main function of the hormone is to regulate the body’s energy levels by sending signals to the hypothalamus, a part of your brain to help maintain a healthy body weight.

When the leptin level decreases, the brain gets a signal that you are hungry and that you should eat food. In addition, changes in the percentage of fat in your body is directly linked with the amount of leptin in your body – because leptin is stored in fat cells.

Your leptin levels increase if you gain body fat. Similarly, if the percentage of fat in your body decreases when you lose weight, leptin levels also go down.

What’s the difference between leptin and ghrelin?

Ghrelin, also known as the “hunger hormone” is primarily produced by the stomach and small intestine. The main function of the hormone is to stimulate appetite which causes you to eat more and store more fat. Ghrelin plays a pivotal role in releasing insulin and keeps your heart health in check.

While it may make sense to think that obese individuals have higher levels of ghrelin which causes them to eat more, it is actually the complete opposite. The levels of ghrelin are actually not higher in people who are overweight. Overweight individuals are just more sensitive to the hormone. On the contrary, they are sensitive to the effects of leptin.

The two hormones actually work together to maintain your body weight. In a healthy body ghrelin ensures that you do not forget to eat and lose too much weight. Whereas leptin tells you when you are full and that you should stop eating.

However, if your body does not respond to ghrelin and leptin, it can disrupt the signals being sent to your brain, causing you to feel hungry more often than normal.

What causes a decrease in leptin levels?

When your body burns more energy than it is taking in, for example, when you are on a weight loss diet or working out, causing you to lose body fat – this causes a decrease in the levels of leptin in your body.

Leptin is mainly produced by the fat cells, so when your body does not have enough fat, it physically cannot produce the same amount of leptin. Your brain is no longer getting signals that you are full and that you should stop eating.

This causes an insatiable hunger even when it is time to eat, making losing weight almost impossible. While you are burning extra body fat and losing weight, the fat in your body is also decreasing, causing a decrease in the production of leptin hormone.

The leaner you are, the less leptin your body has, meaning your appetite will only increase in the long run.
It is quite common for people to go on a diet and lose weight for the first few weeks, however, bounce back and even gain more weight because of insatiable hunger.

This is because of the changes in your leptin levels. In addition to this, testosterone, thyroid hormone, cold temperatures and fasting also reduce leptin levels.

Leptin Resistance and how to increase leptin

Low levels of leptin are not necessarily the problem. An inability of your body to effectively respond to leptin also plays an important role in weight gain. Leptin resistance is a condition in which your body’s sensitivity to leptin decreases.

Your body is not sending signals to the brain that you have enough fat and that your energy needs are fulfilled so you should stop eating. When the brain is not receiving these signals, you do not only lose appetite, but your brain also decreases energy levels to conserve energy.

As a result, you feel less motivated to exercise, which is a key aspect for maintaining a healthy weight, and you end up feeling hungry more often.

Causes of leptin resistance and how to increase leptin

One of the main causes of leptin resistance is obesity. Even though people who are obese have more fat cells in their body, as a result higher leptin levels compared to lean people, their body’s ability to send signals to the brain is disrupted.

The high level of inflammation in the body makes it difficult for leptin to bind to the leptin receptors in the brain. When you have high level of fat in the body, especially around the belly, the fat produces cytokines, which are inflammatory compounds that circulate through the blood and block the effects of leptin, causing leptin resistance.

In conclusion, when the levels of leptin in your body are consistently high it produces leptin resistance.

Leptin resistance and diet

Increasing the amount of leptin in your body does not have much to do with how your body responds to leptin. In addition to this, the food you eat also has a direct impact on how well your body responds to leptin. According to a study1, white pasta, white bread and sugar may cause leptin resistance and a diet rich in fiber-rich carbohydrates, for example, non-starchy vegetables can cause a decrease in both leptin and insulin resistance.

In addition to this, diets that are high in protein and fat also increase leptin sensitivity, as a result, improving leptin resistance2. Protein also increases the levels of testosterone in addition to boosting the levels of leptin directly. Testosterone helps prevent leptin resistance by building muscle, helping you lose weight3.

Ways to keep leptin levels regulated

Fiber-rich diet
Increasing your daily intake of fiber by eating fiber-rich foods, such as, oatmeal, whole grains and legumes can help the brain release more leptin. Fiber makes you feel fuller and causes the intestinal tract to send a signal to the brain to release more leptin.

Limit consumption of fructose

Fructose, especially high-fructose corn syrups inhibit leptin receptors. The main culprit when it comes to leptin resistance is processed foods. Fructose is commonly used in cookies, sodas and other sugary snacks because of how inexpensive it is. The easiest way to limit your fructose intake is to cut down on processed foods and eat whole foods. Whole foods are foods that most closely resemble their natural state.

Add complex carbohydrates to your diet

Limit your intake of white, processed, sugary and refined carbohydrates, also known as simple carbohydrates. These cause an increase in the levels of insulin in your body, leading to insulin resistance. As a result, insulin resistance disrupts the production of leptin.

Complex carbohydrates, such as fruits and vegetables are a great source of fiber and water. Increasing your diet in complex carbohydrates will tell your brain that you are full without having a very high calorie intake. Adding brown rice, quinoa, pastas and oats in moderation will also help achieve this goal.

Have proteins for breakfast

Protein is not only a great source of fuel, but it also helps you feel fuller for longer. In addition to this, it also kickstarts your leptin levels. However, do not rely on cereals too often because they contain high amounts of lectin that can bind to leptin receptors and disrupt leptin’s ability to do its job.

Increase intake of omega 3

Increasing your intake of omega 3 fatty acids either with your diet or with the help of supplements can help increase leptin levels by supporting a healthy inflammatory response. Foods that are rich in omega 3 fatty acids include sardines and salmon.

The fatty acids increase your body’s sensitivity to leptin and make it more receptive.

Don’t restrict your calorie intake

If your body is not getting enough nutrients, it will start shutting down and disrupt the production of leptin hormone. This will cause your metabolism to slow down and decrease the production of leptin. Being at a healthy weight will help regulate your hormones.

Perform high intensity interval training

High intensity workouts stimulate secretions of human growth hormones. As a result, it boosts the fat burning mechanism and helps in regulating leptin levels. Exercising regularly is one of the biggest predictors of long-term weight management.

Although, this does not mean that you run 5 miles a day. Any exercise routine counts as long as you are consistent with it. it can be anything from walking to work to using the stairs instead of the elevator or just doing some jumping jacks while watching tv.

Get a good night’s sleep

Getting at least 8 hours of sleep a night is recommended. If your body is not getting enough rest, it will produce less leptin and more ghrelin, telling your body that you are hungry. In addition to this, your body starts producing ghrelin and not leptin.

According to a recent study, those who did not get good sleep at night had 15% lower leptin levels compared to those who did. This is because leptin levels typically rise during the sleep cycle4. Leptin is an important hormone for maintaining weight.

Keeping your leptin levels in a healthy range will help keep your body in the best shape in the longer run and help you manage your appetite.

Work on stress management

Stress increases the level of cortisol (stress hormone) in your body. Cortisol can make the brain less receptive to leptin. Stress affects everyone differently, however, if you are living in a constant state of stress, your goal body weight will become out of the question.

Stress does not only affect your metabolism, but it also raises the amount of blood sugar in your body. In addition to this, it triggers behavior patterns, such as, skipping workout sessions and eating comfort food that may not align with long-term goals.

Whether it’s taking a walk during your break from work or starting meditation, it is important to incorporate stress-management practices in your routine to help you stay calm and on track.

Cut down on alcohol to increase leptin

While you don’t completely have to cut down on alcohol to lose weight, it is important that you count your drinks. Set a limit on how much you are going to drink and make it a smaller one.

This is something that is easy to overdo without you realizing how many calories you are consuming. If you are eating healthy all day but having multiple drinks in the evening – you are undoing all your day’s hard work. It is important that you log your food and drinks, so you have an idea of how many calories you are consuming in a day.

Reaching your goal weight does not mean you have to give up on alcohol, however, being mindful of your drink choices can help you find a healthy balance.

Do supplements help with leptin resistance?

Most supplements that claim to regulate the levels of leptin in your body do not actually contain the hormone itself. While most supplements that are available in the market are labelled as “leptin pills”, they generally contain a mix of various nutrients that reduce inflammation, therefore, increase leptin sensitivity5.

Some ingredients the supplements include are alpha-lipoic acid6 and fish oil. Whereas others may contain conjugated linoleic acid7, soluble fiber and green tea extract.

There are many studies that involve weight loss supplements, however, their effect on improving leptin resistance still needs to be explored further. Researches have also shown that African mango has a positive effect on weight loss and leptin sensitivity.

It has been shown to decrease the levels of leptin, thereby, improving sensitivity8. Studies have also concluded that African mango helps with reducing weight and decreasing weight circumference9. However, there is a need for more research to conclude whether supplements help decrease leptin resistance.

Find support

You may think that losing weight is a personal project. Having a team of supporters can actually make a huge difference. Sign up with a daily or weekly individual group support to help you find a squad that will help motivate you to make healthier choices at the grocery store and plan workouts. This will help you hit your weight loss milestone sooner than you think!

References
1.Izadi, V., Saraf-Bank, S. and Azadbakht, L., 2014. Dietary intakes and leptin concentrations. ARYA atherosclerosis, 10(5), p.266.
2.Vasselli, J.R., Scarpace, P.J., Harris, R.B. and Banks, W.A., 2013. Dietary components in the development of leptin resistance.
3.Traish, A.M., 2014. Testosterone and weight loss: the evidence. Current opinion in endocrinology, diabetes, and obesity, 21(5), p.313.
4.Chaput, J.P., Després, J.P., Bouchard, C. and Tremblay, A., 2007. Short sleep duration is associated with reduced leptin levels and increased adiposity: results from the Quebec family study. Obesity, 15(1), pp.253-261.
5.Sáinz, N., González-Navarro, C.J., Martínez, J.A. and Moreno-Aliaga, M.J., 2015. Leptin signaling as a therapeutic target of obesity. Expert Opinion on Therapeutic Targets, 19(7), pp.893-909.
6.Li, N., Yan, W., Hu, X., Huang, Y., Wang, F., Zhang, W., Wang, Q., Wang, X. and Sun, K., 2017. Effects of oral α‐lipoic acid administration on body weight in overweight or obese subjects: a crossover randomized, double‐blind, placebo‐controlled trial. Clinical endocrinology, 86(5), pp.680-687.
7.Medina, E.A., Horn, W.F., Keim, N.L., Havel, P.J., Benito, P., Kelley, D.S., Nelson, G.J. and Erickson, K.L., 2000. Conjugated linoleic acid supplementation in humans: effects on circulating leptin concentrations and appetite. Lipids, 35(7), pp.783-788.
8.Ross, S.M., 2011. African mango (IGOB131): a proprietary seed extract of Irvingia gabonensis is found to be effective in reducing body weight and improving metabolic parameters in overweight humans. Holistic nursing practice, 25(4), pp.215-217.
9.Ngondi, J.L., Etoundi, B.C., Nyangono, C.B., Mbofung, C.M. and Oben, J.E., 2009. IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation. Lipids in Health and Disease, 8(1), p.7.

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