Intermittent Fasting and Leptin Resistance Intermittent Fasting and Leptin Resistance. Intermittent fasting may be a key to reducing leptin resistance and other fat-related problems. Fasting can lower adiponectin, ghrelin, and inflammation. It also promotes leptin sensitivity. However, a person’s genetics and lifestyle can also contribute to leptin resistance. Intermittent fasting reduces leptin resistance The dietary…
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